.五种海马提取物对L—谷氨酸致大鼠神经元钙内流的拮抗作用[J].中国海洋药物,1994,13(4):6-9. |
五种海马提取物对L—谷氨酸致大鼠神经元钙内流的拮抗作用 |
INHIBITORY EFFECTS OF HIPPOCAMPUS SPP. EXTRACTS ON L-GLUTAMIC ACID INDUCED Ca~(2+)INFLUX IN RATS''''NEURONS |
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DOI: |
中文关键词: 钙离子 神经元 尼莫地平 海马 L-谷氨酸 |
English Keywords:Calcium iron,Neurons,Nimodipine,Hippocampus spp. |
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中文摘要: |
用Fura—2/AM测定细胞内钙离子浓度,结果表明,5种海马提取物对L—谷氨酸致大鼠神经元钙内流有明显的抑制作用。其中大海马H.kuda的抑制作用最强,日本海马作用最弱,这与传统药材质量评价相一致。 |
English Summary: |
Application of Fura - 2/AM measured the calcium concentration [Ca~(2+)] and the significant inhibitory effects of the extracts of 5 species of Hippocampus on exitatory amino acid L - glutamic acid induced Ca2+ influx in rats'neurons have been reported. The extracts from H. kuda showed the strongest effects and the extract from H. japonicus did weakly. This results are in line with traditional medical material quality evaluation. |
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