.藻酸双酯钠和曲克芦丁治疗假性延髓麻痹的比较[J].中国海洋药物,1995,14(4):30-33.
藻酸双酯钠和曲克芦丁治疗假性延髓麻痹的比较
A COMPARATIVE STUDY OF PSS AND TROXERUTIN IN THE TREATMENT OF PSEUDOBULBAR PARALYSIS
  
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中文关键词:  曲克芦丁 脑梗死 假性延髓麻痹 藻酰双酯钠
English Keywords:Polysaccharide Sulphate (PSS ),Troxerutin (TR ),Cerebral infarction,Pseudobulbar paralysis
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中文摘要:
      对藻酸双酯钠和曲克芦丁治疗缺血性脑梗死致假性延髓麻痹152例患者的临床疗效和实验室变化进行了对比研究,其中76例,用PSS150mg溶于5%葡萄糖溶液500mL,iv,drip,qd,14d为一个疗程;另76例,用TR600mg加入6%羟乙基淀粉500mL,iv,drip,qd,14d为一个疗程。结果表明,PSS总有效率94.74%,TR为77.63%;PSS组治疗后胆固醇、甘油三酯均有显著下降。
English Summary:
      152 patients with pseudobulbar paralysis resulting from ischemic cerebral infarction were treated with polysaccharide sulphate (PSS) or Troxerutin (TR) and their clinical curative effect and laboratory parameters were studied. 76 patients (M46,F30,mean ages 62+6 y),were treated with PSS:PSS 150 mg in 5% Glocose Solution 500 mL iv. drip. qd,for 14 days as a course. The other 76 patients (M46,F30,mean age 63 + 7 y) were treated with (TR);TR 600 mg in hydroxyethyi-starch 500 mL iv. drip ,qd .for 14 days as a course. The results showed that the total effective rates of the two groups were 94. 74% and 77. 63% .respectively. Moreover the plasma levels of cholesteral and triglyceride were decreased significantly ( P < 0. 001). It indicates that PSS is worth using widely in the treatment of pseudobulbar paralysis caused by ischemic cerebral infarction.
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