.条斑紫菜提取液的降血脂作用及其临床观察[J].中国海洋药物,1998,17(2):43-45.
条斑紫菜提取液的降血脂作用及其临床观察
EFFECT OF THE EXTRACT FROM PORPHYRA YEZOENS IS UEDA ON HYPERLIPEMIA AND CLINICAL OBSERVA TION
  
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中文关键词:  治疗前 对照组 提取液 高脂血症 临床观察 降血脂作用 TC 条斑紫菜 饲喂 下降
English Keywords:extract from Porphyra yezoensis Ueda (EPY) , hyperlipemia,hypolipemic-effect,clinical observation
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中文摘要:
      用条斑紫菜提取液饲喂高脂血症大鼠20d后,总胆固醇(TC)比对照组下降24%(P<0.01);临床观察显示,高脂血症患者口服条斑紫菜提取液6w后,其TC、甘油三酯(TG)、低密度脂蛋白(LDL)、载脂蛋白B(ApoB)较治疗前分别下降16%、20.7%、26.2%、13.8%,而高密度脂蛋白(HDL)、载脂蛋白A-I(ApoA-Ⅰ)则较治疗前分别上升32.4%和34.5%,疗效优于对照组(P<0.05)。结果表明,条斑紫菜提取液具有降血脂、防止动脉粥样硬化的功能,且无任何毒副作用。
English Summary:
      When extract from Porphyra yezoensis Ueda(EPY) was fed to mice with hy-perlipemia for 20 days,the total cholesterol (TO decreased by 24% .comparing to control group (P<0. 01). Clinical observation showed that the total cholesterol, triglyceride, low density lipoprotein (LDL) ,apoprotein B decreased by 16%,20. 7%,26- 2%, 13. 8%,respectively and the high density lipoprotein ,apoprotein A-I increased by 32- 4%, 34,5% respectively, when EPY was taken by the patient with hyperlipemia. The hypolipemic effect was better in EPY group than that of control group (P<0. 05). It concluded that EPY has effects of decreasing blood-fat,preventing atherosclerosis and there was no any side effect.
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