.复方5-氟尿嘧啶多烯酸胶囊剂抗癌活性的研究[J].中国海洋药物,2003,22(6):19-22. |
复方5-氟尿嘧啶多烯酸胶囊剂抗癌活性的研究 |
Study of compound 5-FU polyunsaturated fatty acids capsule on the anti-cancer activities in mice |
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DOI: |
中文关键词: 5-氟尿嘧啶 多烯不饱和脂肪酸 复方胶囊 抗癌活性 |
English Keywords:5-Fluorouracil(5-FU),polyunsaturated fatty acids,compound capsule,anti-cancer activity, |
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中文摘要: |
以小鼠肉瘤180(S180)、肝癌实体瘤(Heps)、艾氏实体瘤(EAC)为模型,对经筛选的复方5-FU多烯酸胶囊剂3个剂量进行抗癌活性研究,实验结果表明:复方5-FU多烯酸胶囊剂对S180、肝癌实体瘤的抑瘤率较市售5-FU片剂提高l0%左右.对EAC的生命延长率较市售片剂显著提高。 |
English Summary: |
With the pharmacodynamic model of S 180 , EAC, Heps tumor in mice, the inhibiting rate of S 180 , Heps at three doses of the compound 5-FU polyunsaturated fatty acids capsules were about ten percent higher than that of the tablet. The prolonged life span of EAC-bearing mice at three doses of the compound 5-FU polyunsaturated fatty acids capsules were evidently greater than that of the tablet. |
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