| 宋小雨,玄光善,于广利.岩藻聚糖硫酸酯药理学活性研究进展[J].中国海洋药物,2017,36(1):92-97. |
| 岩藻聚糖硫酸酯药理学活性研究进展 |
| Research advances of pharmacological activities of fucoidan |
| 投稿时间：2016-05-09 修订日期：2016-06-17 |
| DOI： |
| 中文关键词: 岩藻聚糖硫酸酯 药理学活性 综述 |
| English Keywords:fucoidan pharmacological activity review |
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| 中文摘要: |
| 岩藻聚糖硫酸酯是一类来源于褐藻且结构复杂的海洋硫酸多糖，主要由硫酸化岩藻糖、半乳糖、甘露糖、葡萄糖醛酸及少量葡萄糖和木糖组成。研究表明，岩藻聚糖硫酸酯具有抗凝血与促凝血、抗炎、抗肿瘤、抗氧化、抗病毒、抗菌、免疫调节、降血脂、降血糖、抗补体及促进肠道益生菌生长等多种药理学活性。本文对岩藻聚糖硫酸酯的上述活性进行了综述，并对其应用前景进行展望，为其深度开发利用提供有用参考。 |
| English Summary: |
| As a marine sulfated polysaccharide mainly derived from brown alga, fucoidan has a complex structure which is mainly composed of sulfated fucose, galactose, mannose, glucuronic acid, and small amount of glucose and xylose. Previous studies have demonstrated diverse pharmacological activities of fucoidan including: anticoagulation, procoagulation, antinflammation, anticancer, antioxidant, antivirus, antibacterial, immunoregulation, antihyperlipidemic, antihyperglycemic, anticomplement and prebiotic effects on gut microbiota. Here we give an up-to-date review on the pharmacological activities of fucoidan and its prospect of applications in the future. We hope this review will benefit the deep development and utilization of fucoidan. |
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