| .褐藻糖胶的免疫调节作用[J].中国海洋药物,1995,14(3):9-13. |
| 褐藻糖胶的免疫调节作用 |
| AN EXPERIMENTAL STUDY ON IMMUNOREGULATORY EFFECT OF FUCOIDAN |
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| DOI： |
| 中文关键词: 褐藻糖胶 免疫调节 |
| English Keywords:Fucoidan,Immunoregulatory effect |
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| 中文摘要: |
| 观察了从海带中提取的褐藻糖胶对小鼠免疫功能的影响，褐藻糖胶在体外可诱导白细胞介素１（ＩＬ－１）和丙型干扰素（ＩＦＮ－γ）产生；体内给药可增强Ｔ细胞，Ｂ细胞，巨噬细胞（Ｍ）和自然杀伤细胞（ＮＫ细胞）功能，促进对绵羊红细胞（ＳＲＢＣ）的初次抗体应答。 |
| English Summary: |
| Funcoidan (FCD) is a polysaccharide extracted from Laminaria japonica Aresh. When we injected FCD into mice subcutaneously for 9 days in our experiments, splenocyte proliferation induced by mitogen (Con A, PHA, LPS), IL - 1 production of peritoneal M?induced by Lps and IL - 2 production of splenocyte induced by Con A were promoted and the primary antibody response to SRBC of murine splenocyte was also promoted. FCD could directly stimulated murine splenocyte to produce IFN - 7. FCD, in vitro or in vivo ,could enhance NK activity. |
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