.羟基化壳聚糖衍生物的制备及其抗凝血性能[J].中国海洋药物,1997,16(2):13-15. |
羟基化壳聚糖衍生物的制备及其抗凝血性能 |
PREPARATION OF HYDROXYL-CHITOSAN DERIVATIVES AND THEIR ANTICOAGULANT EFFECT |
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中文关键词: 羟基化壳聚糖 衍生物 制备 抗凝血 壳聚糖 |
English Keywords:hydroxyl-chitosan derivatives,preparation,anticoagulant effect |
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中文摘要: |
合成了几种羟基化壳聚糖衍生物,并观察了它们的抗凝血性能。凝血时间和复钙时间的测定结果表明,与玻璃和硅油涂层玻璃相比,衍生物有较好的抗凝血性能。衍生物的凝血时间与其特性粘度有关。 |
English Summary: |
The several derivatives of hydroxyl-chitosan were prepared and their anticoagulant effect was investigated. The measurement results of clotting time and plasma racalcifi-cation time in vitro showed that the anticoagulant effect of the derivatives was higher than that of glass and siliconized glass. The clotting time on the derivatives surface d.epended on its intrinsic viscosity. |
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