| .河豚卵巢提取物对小鼠免疫功能的影响及抑瘤初探[J].中国海洋药物,2000,19(2):24-27. |
| 河豚卵巢提取物对小鼠免疫功能的影响及抑瘤初探 |
| EFFECT OF EXTRACT FROM FUGUS OVARY ON IMMUNE FUNCTION OF MICE AND EARLY STUDY OF ITS′ INHIBITIVE EFFECT FOR SARCOMA |
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| DOI： |
| 中文关键词: 河豚 卵巢提取物 蚕噬作用 抑瘤作用 |
| English Keywords:Extract from fugus ovary,Phagocytic function,Agglutination,Hemolysis, Inhibitive effect for sarcoma |
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| 中文摘要: |
| 研究发现河豚卵巢提取物具有一定的免疫功能和生物活性。动物实验结果表明：注射不同浓度的提取物可明显增加小鼠脾脏和胸腺的重量（Ｐ〈０．０１）；提出小鼠腹腔巨噬细胞和吞噬指数（Ｐ〈０．０１）及提高由ＳＲＢＣ致敏的血凝素抗体的效价（Ｐ〈０．０１）；对小鼠外周血清溶血素的无明显影响（Ｐ〉０．０５）。由此推测该提取物对免疫系统的不同环节，作用不同。且在一定剂量下对小鼠实体瘤Ｓ１８０的抑制率为４５．８％。 |
| English Summary: |
| The immunologic function and bioactivity of extract from fugu ovary has been studied' Given ip different dose of extract, the spleen and thymus weight of mice (P<0.01),phagocytic rate and phagocytic index (P< 0.01) were increased significantly (P< 0.01).Meanwhile the serum agglutinin antibody valence immuned by SRBC was increased significantly (P< 0.01), and the serum hemolysin was no significantly (P< 0.05). The results show that extract from fugu ovary has different effects on different linkage of the immunologic system. And in a certain dosage, for solfd form of sarcoma S180 of mice,its' inhibiting rate is 45. 0%. |
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