| .褐藻糖胶抗血栓研究进展[J].中国海洋药物,2002,21(2):53-59. |
| 褐藻糖胶抗血栓研究进展 |
| Study progresses on the antithrombotic activities of fucoidan |
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| DOI： |
| 中文关键词: 褐藻糖胶 抗血栓 抗凝血 |
| English Keywords:Fucoidan,Antithrombosis,Anticoagulant |
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| 中文摘要: |
| 褐藻糖胶是一种酸性硫酸化多糖，有多种生物活性和药理作用，其抗血栓活性尤为明显。褐藻糖胶能够抑制凝血酶的产生及活性，提高组织型纤溶酶原活化剂对纤溶酶原的激活作用，从而具有抗血栓形成和溶栓功能。 |
| English Summary: |
| Fucoidans, the acid polysaccharides with sulfate ester, have many biological properties and pharmacological functions. Its antithrombotic activity is especially potent. Fu-coidans have both antithrombotic and fibrinolytic properties by inhibiting the generation and the activity of thrombin, and by enhancing the activation of plasminogen by tissue plasmino-gen activator (t-PA). |
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