| .孔石莼多糖降血脂活性的初步研究[J].中国海洋药物,2003,22(2):33-35. |
| 孔石莼多糖降血脂活性的初步研究 |
| A preliminary study on antilipemic activity of polysaccharides from Ulva pertusa in mice |
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| DOI： |
| 中文关键词: 孔石莼多糖 降血脂活性 研究 高脂血症 生物活性 |
| English Keywords:Ulva pertusa Kjellm.,polysaccharides,hyperlipemia,antilipemic,biological activity |
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| 中文摘要: |
| 为开发我国的孔石莼资源，在研究了其多糖化学组成的基础上，进行了孔石莼多糖对高脂血症的活性研究。结果表明：3个剂量的多糖样品组均有显著的降甘油三酯作用；中、高剂量组可显著降低血清中总胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)，升高高密度脂蛋白胆固醇(HLD-C)从而增加HDL—C／TC的比值；高剂量组的降脂活性与阳性对照药烟酸肌醇酯相近；血清中脂蛋白胆固醇的改善状况有明显的剂量依赖性。并对孔石莼多糖降血脂活性的机理进行了讨论。 |
| English Summary: |
| The antilipemic activity of ulvan in mice was studied based on the study of the physico-chemical properties of ulvan (polysaccharides from Ulva pertusa). The result revealed that three ulvan dose groups had significant activity to lower the levels of TG; Both middle and high dose groups can lower the levels of TC,TG,LDL-C and increase HDL-C/TC in the serum. High dose group also can enhance HDL-C content significantly. Effects of ulvan on LDL-C,HDL-C,. HDL-C/TC were dose-dependent. The activity of high dose ulvan group was very similar to the positive control group in the same dose. |
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