.4种南极冰藻中抗紫外辐射活性化合物类菌胞素类氨基酸(MAAs)的初步研究[J].中国海洋药物,2007,26(4):5-10. |
4种南极冰藻中抗紫外辐射活性化合物类菌胞素类氨基酸(MAAs)的初步研究 |
Preliminary study on the antiultraviolet irradiation active substances of mycosporine-like amino acids from four kinds of Antarctic ice microalgae |
修订日期:2007-01-28 |
DOI: |
中文关键词: 南极冰藻 紫外辐射 类菌胞素类氨基酸 |
English Keywords:Antarctic ice microalgae,ultraviolet irradiation,mycosporine-like amino acids(MAAs) |
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中文摘要: |
目的研究和发现极端环境下南极冰藻中抗紫外辐射活性化合物。方法对4种生长较快的南极冰藻进行低温光照培养,同时采用UV-A和UV-B辐照胁迫,提取分离抗紫外辐射活性化合物;根据其理化性质、仪器分析数据初步确定各化合物的分子结构。并通过日光辐照活性组分,观察其降解速度,确定其抗紫外辐射活性。结果从南极绿藻Chlorophyceae L-4,硅藻Diatom HF-9中分别得到5种、7种活性化合物,其中6种属于类菌胞素类氨基酸(MAAs)类物质,并具有较强的抗紫外辐射活性。结论MAAs类物质在南极冰藻抗强紫外辐射过程中扮演重要角色。 |
English Summary: |
Objective To study on bioactive chemical compounds against ultraviolet irradiation in antarctic ice microalgae.Methods Four kinds of Antarctic ice microalgae were cultured under the conditions of low temperature,illumination,UV-A and UV-B irradiation.The chemical compounds were extracted by methanol and analyzed by spectrophotometer and HPLC/MS.The molecular structures were elucidated according to these data.The chemical compounds were irradated by sunshine to observe the speed of degradation and to estimate the bioactivity.Results There were five active compounds in Chlorophyceae L-4 and 7 active compounds in Diatom HF-9,in which 6 compounds belong to MAAs(mycosporine-like amino acids) and were of more bioactivity against ultraviolet irradiation.Conclusion MAAs from of Antarctic ice microalgae play an important role in resisting ultraviolet irradiation. |
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