| 顾兴宇,白光辉,刘璐,等.海参多糖结构表征的研究进展[J].中国海洋药物,2023,42(1):66-75. |
| 海参多糖结构表征的研究进展 |
| Research Progress on structural characterization of sea cucumber polysaccharide |
| 投稿时间：2022-01-27 修订日期：2022-02-23 |
| DOI： |
| 中文关键词: 海参多糖 分析方法 结构表征 |
| English Keywords:Sea cucumber polysaccharide analytical methods structural characterization |
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| 中文摘要: |
| 海参多糖是一种富含硫酸基团的杂多糖,结构十分复杂,具有多种生物活性,其生物活性与海参多糖本身的化学组成、分子量、硫酸化模式等结构特征息息相关。因此,为了更好的研究海参多糖的生物活性,本文全面总结了海参多糖结构的分析方法,并且综述了海参中性聚糖、海参岩藻糖基化硫酸软骨素和海参岩藻聚糖硫酸酯的结构特征,以期为海参多糖的生物活性及构效关系等后续研究提供理论基础。 |
| English Summary: |
| Sea cucumber polysaccharide is a kind of heteropolysaccharide rich in sulfate groups. It has complex structures and various biological activities. Its biological activity is closely related to its chemical composition, molecular weight, and sulfated patterns. Therefore, in order to better study the biological activity of sea cucumber polysaccharide, this paper comprehensively summarizes the analysis methods of sea cucumber polysaccharide structure, and reviews the neutral polysaccharide, fucosylated chondroitin sulfate and sulfated fucan of sea cucumber. The structural characteristics of sea cucumber polysaccharide are expected to provide a theoretical basis for subsequent studies on the biological activity and structure-activity relationship of sea cucumber polysaccharide. |
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